Article by: Austin Rhoads
Austin is the Co-Founder of Alterra Health and has been a leader in the development of weight loss education programs for patients and medical practitioners since 2018.
Not losing weight with GLP-1? GLP-1 medications, or glucagon-like peptide-1 receptor agonists, have gained popularity in recent years for their effectiveness in managing type 2 diabetes and aiding in weight loss. Examples of common GLP-1 drugs for medical weight loss include Ozempic, Semaglutide, Wegovy, Mounjaro, Zepbound, Tirzepatide, Liraglutide, Saxenda, and more. Despite their proven efficacy for many individuals, some patients may find themselves frustrated if they’re not experiencing the weight loss they expected. If you’re in this situation and are not losing weight with GLP-1 medications, don’t lose hope. There are several factors to consider and strategies to implement to potentially overcome this obstacle. In this article, we’ll delve into why weight loss might stall on GLP-1 medications and explore practical steps to address it.
1) Understanding GLP-1 medications.
Before delving into troubleshooting, it’s crucial to understand how GLP-1 medications work and their effects on weight. GLP-1 receptor agonists function by mimicking the action of the natural hormone GLP-1, which stimulates insulin secretion, reduces glucagon secretion, and slows gastric emptying. These actions contribute to improved blood sugar control and, importantly, can lead to weight loss in many individuals. However, the degree of weight loss can vary among patients, and some may not experience significant changes despite adhering to treatment.
2) Reasons for weight loss plateaus on GLP-1 medications.
Several factors can contribute to a plateau in weight loss while taking GLP-1 medications. Understanding these factors is crucial for devising an effective strategy to overcome the obstacle:
• Metabolic adaptation: Initially, GLP-1 medications may lead to rapid weight loss as they affect appetite and food intake. However, the body can adapt to these changes over time, leading to a plateau in weight loss.
• Caloric intake: Despite the appetite-suppressing effects of GLP-1 medications, some individuals may unknowingly compensate by increasing their caloric intake. Overeating can counteract the medication’s weight loss benefits.
• Physical activity levels: While GLP-1 medications can enhance weight loss efforts, they are most effective when combined with a healthy diet and regular exercise. Insufficient physical activity may hinder weight loss progress.
• Insulin resistance: GLP-1 medications primarily target individuals with type 2 diabetes, many of whom have insulin resistance. In such cases, insulin resistance can make weight loss more challenging, even with the assistance of GLP-1 medications.
• Medical conditions & medications: Certain medical conditions and medications can interfere with weight loss efforts. For instance, hypothyroidism, polycystic ovary syndrome (PCOS), or antidepressants may affect metabolism and body weight.
3) Strategies to break through the plateau if you’re not losing weight with GLP-1 medications.
If you’re not losing weight on GLP-1 medications, don’t despair. There are several steps you can take to reignite your weight loss journey:
• Review your diet: Keep a detailed food diary to track your daily caloric intake. Be mindful of portion sizes and avoid high-calorie, low-nutrient foods. Consider consulting a registered dietitian for personalized dietary advice.
• Increase physical activity: Aim for at least 150 minutes of moderate-intensity aerobic activity per week, such as brisk walking, cycling, or swimming. Additionally, incorporate strength training exercises to build muscle mass, which can boost metabolism.
• Monitor blood sugar levels: Fluctuations in blood sugar levels can affect appetite and cravings. Monitor your blood sugar regularly and work with your healthcare provider to adjust your medication regimen if necessary.
• Address underlying medical conditions: If you have coexisting medical conditions that may impact weight loss, such as hypothyroidism or PCOS, ensure they are properly managed. Work closely with your healthcare team to optimize treatment.
• Evaluate medications: Some medications can cause weight gain or hinder weight loss efforts. If you suspect that your current medications are affecting your weight, discuss alternative options with your healthcare provider.
• Practice mindful eating: Pay attention to hunger and fullness cues, and avoid eating in response to emotions or external cues. Practice mindful eating techniques such as chewing slowly and savoring each bite.
• Consider psychological factors: Emotional eating, stress, and poor sleep can all influence weight management. Prioritize self-care activities, such as meditation, yoga, or therapy, to support your mental well-being.
• Set realistic goals: Instead of focusing solely on the number on the scale, celebrate non-scale victories such as increased energy levels, improved fitness, or better blood sugar control.
Lack of weight loss while taking GLP-1 medications can be frustrating, but it’s essential to approach the situation with patience and perseverance. By identifying potential barriers to weight loss and implementing targeted strategies, you can break through the plateau and continue progressing toward your health goals. Remember to work closely with your healthcare provider to tailor a comprehensive treatment plan that addresses your individual needs and circumstances. With dedication and support, you can achieve sustainable weight loss and improve your overall health and well-being.
Weight loss plateaus are a common but often frustrating aspect of the GLP-1 medical weight loss journey… If you’re feeling stuck and need help to continue making progress, download our free guide here to help you get back on track!
Alterra Health and its parent company Puente Holdings, LLC provide education, coaching, guides, support, and programs for patients. Individual results may vary. This article should not be construed as medical advice. For all clinical questions, please consult your medical provider.